ARCHIVES
VOL. 9, ISSUE 1 (2024)
A comprehensive review on skin as a route of administration
Authors
Ashwini S Kamble, Rutuja D Shitole, Komal A Virkar, Pratiksha M Mane
Abstract
At two meters square meters, the skin is the biggest organ in the body.
Basically, the epidermis, dermis, and hypodermis are the three separate layers
that make up the skin. Protecting the body from unwelcome environmental
influences is the skin's natural purpose. For a variety of reasons, the skin
presents a particularly alluring substitute delivery system. The skin Ensure
that the location where medication is administered is easily accessible and
convenient. A desirable substitute for traditional injection for the
administration of vaccines and other treatments is the use of transdermal drug
delivery systems, which relate to the passage of medication via the skin.
Patient acceptance and compliance with transdermal drug administration devices
are good. Pharmaceutical delivery that is painless and less invasive is made
possible via transdermal drug delivery system. Moreover, it prevents the
first-pass action of the liver and GIT degradation, which are frequently linked
to oral prescription. Because of its permeability and ability to shield the
body from outside agents, the stratum corneum, the top layer of the epidermis,
is primarily composed of lipids. Not only is skin noninvasive and convenient,
but it also acts as a reservoir to maintain delivery over several days. In
comparison to traditional drug administration methods, the transdermal route
offers no benefits, such as avoiding the first pass impact. Improved patient
compliance, painless medication delivery, increased bioavailability, and simple
patch removal in the event of toxicity.
Pages:56-60
How to cite this article:
Ashwini S Kamble, Rutuja D Shitole, Komal A Virkar, Pratiksha M Mane "A comprehensive review on skin as a route of administration". International Journal of Research in Pharmacy and
Pharmaceutical Sciences, Vol 9, Issue 1, 2024, Pages 56-60
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